Russia’s 75th Arsenal hit in Serpukhov as Ukraine reports record Russian losses: 22 October 2026
The 75th Arsenal in Serpukhov, Moscow region, came under attack overnight into 22 October. The facility repairs and stores Russian surface-to-air missile systems. Ukraine’s General Staff also reported the highest daily Russian personnel losses since the full-scale invasion began, while the Unmanned Systems Forces announced a record of their own.
Demilitarizator has compiled the main reports on strikes against Russian facilities and Ukrainian defence operations published on 22 October 2026.
Attack on the 75th Arsenal in Serpukhov: what is known
Explosions were heard in Serpukhov, in the south of Moscow region, overnight into 22 October following a strike on the grounds of the 75th Arsenal.
The 75th Arsenal specialises in repairing, restoring and storing military equipment. Systems serviced at the facility include the Buk-M1, Buk-M2 and S-300V, which the Russian military uses for air defence.
The facility’s importance lies in its ability to return equipment to service. Damage to repair infrastructure could make it harder to restore surface-to-air missile systems and supply them to Russian units.
Overnight explosions in other Russian regions
Monitoring channels reported explosions and air defence activity in Lipetsk, Tula and Moscow region that same night.
Ukraine’s General Staff reports 2,250 Russian personnel casualties in one day
On the morning of 22 October, Ukraine’s General Staff estimated Russian personnel losses for 21 October at 2,250.
It is the highest daily figure since the full-scale invasion began. The previous peak of 2,200 was recorded on 19 December 2024.
Estimated cumulative Russian personnel losses since 24 February 2022 reached 1,572,790.
Drone forces record: 680 Russian troops killed or wounded
The Unmanned Systems Forces grouping recorded a separate high for 21 October. Figures released on 22 October put Russian personnel casualties inflicted by its units at 680, including 320 killed.
The force reported 2,353 enemy targets hit during the day. These included one surface-to-air missile or combined gun-and-missile air defence system, 14 radar and electronic warfare systems, nine artillery systems and 57 drone launch sites.
For 1–21 October, the grouping reported 45,147 targets hit and 11,292 enemy personnel killed or wounded.
How the figures changed
The data may be revised when official statements or further assessment become available.